R. Shapiro's work are mainly on kabbalah: Yayin ha-Meshummar (Venice 1660),on the prohibition against drinking gentile wine (stam yayin) and shaving one’s beard. Italian Jewry was considered lax in their observance of these mitzvot, necessitating this work. These two proscriptions, the former a rabbinic decree based on the Talmud, the other biblical, are codified in the Shulhan Arukh. R. Spira’s approach is kabbalistic, as is that of many of the other contributors to Yayin ha-Meshummar. "Tuv ha-Erez" (Venice, 1655; Zolkiev, 1781), on the excellencies of the Holy Land, on the holy vessels, etc. R. Azulai saw the manuscripts of his religious discourses and of several of his kabalistic works - some were printed at the end of the 19th century.