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R. Issar Judah ben Nehemiah of Brisk (d. 1876) was a Lithuanian rabbi. He lived in Szydlowiec, Brest-Litovsk (Brisk), where he was head of the bet din, and Siedlce. He immigrated to Ereẓ Israel toward the end of his life and died there. He was the author of, in addition to Ezrat Yehudah, Nehamat Yehudah (1866), comprising two parts – Igra de-Shemata, essays on halakhic novellae, and Igra de-Pirka, pilpulistic homilies and novellae which aimed at resolving difficulties in Maimonides' code.